RNA-based therapies are calling for an R&D data management revolution

RNA-based therapies are calling for an R&D data management revolution. Test body.

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For instance, researchers need to be able to design and compare the performance of multiple oligos to improve the chance of identifying one that is particularly efficacious. Screening reveals which chemical modifications offer resistance to nucleases, which oligo length is most stable and specific, and if a stretch of purines in the target sequence stabilizes the heteroduplex. This all generates an abundance of different types of data that needs to be stored, tracked, and analyzed.

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For instance, researchers need to be able to design and compare the performance of multiple oligos to improve the chance of identifying one that is particularly efficacious. Screening reveals which chemical modifications offer resistance to nucleases, which oligo length is most stable and specific, and if a stretch of purines in the target sequence stabilizes the heteroduplex. This all generates an abundance of different types of data that needs to be stored, tracked, and analyzed.

For instance, researchers need to be able to design and compare the performance of multiple oligos to improve the chance of identifying one that is particularly efficacious. Screening reveals which chemical modifications offer resistance to nucleases, which oligo length is most stable and specific, and if a stretch of purines in the target sequence stabilizes the heteroduplex. This all generates an abundance of different types of data that needs to be stored, tracked, and analyzed.