Case Study Case Study Anthology Eleven case studies of how customers used Benchling to level up their R&D capabilities. Learn more
Video SynBioBeta | Benching & Pairwise – The Future of Agriculture Through SynBioBeta's webinar series, Benchling and Pairwise came together to discuss how gene editing allows the production of new and improved crops that are more sustainable, more nutritious, and more affordable. We also covered the challenges and opportunities for using gene editing to bring better food to market. Watch Now
Video The Jennifer Doudna Lab Knocks CRISPR Out of the Park Jennifer Doudna is a world-renowned biochemist at the University of California, Berkeley, best known for her foundational research on CRISPR, a gene editing technology that has transformed biological research in less than a decade. Together, her lab members are working towards another decade of CRISPR innovation. Watch Now
Video Webinar: Codon Optimization with Benchling Species-specific codon usage is an important factor to consider for improving protein expression. In this webinar, we discussed Benchling’s brand new Codon Optimization tool for systematically utilizing abundant tRNAs in various target organisms. We demonstrated how this tool’s powerful functionality, integrated with our Molecular Biology application and our data management platform, can enhance your protein expression workflows. Watch Now
Blog Benchling: Bringing biointelligence to life science R&D We're thrilled to announce Benchling’s Series C fundraising, led by Menlo Ventures and joined by Lead Edge Capital and YC Continuity. In this post, we discuss our plans for Benchling as we enter this new stage of growth, and how biointelligence is crucial for the companies that are redefining modern life science. Learn more
Case Study Adicet Bio: Building a Data Infrastructure for Next-Generation Cell Therapies Adicet Bio is building the next generation of cellular therapies with gamma delta T cells. With Benchling, Adicet Bio now has a data infrastructure that ensures their data's integrity, allows them to efficiently file for IND, and is set to scale as their team grows and their research expands. Learn more
Video Sitting Down with Adicet Bio: Building a Data Infrastructure for Cellular Therapies Watch the interview with Jeannette Grant of Adicet Bio where she shares how Adicet uses Benchling to ensure their data's integrity which prepares them for IND filing and ultimately helps them bring their therapies to the clinic. Watch Now
Video Webinar: High-Throughput DNA Sequence Design for Modern Molecular Biology Workflows Successful companies have embraced the complexity of molecular biology by building collaborative teams to carry out high-throughput research. These teams urgently need automated sequence design and analysis tools. Watch this webinar to see how Benchling Bulk DNA Assembly — a tool for modeling high-throughput combinatorial cloning in silico — accelerates molecular biology workflows. Watch Now
Video A Conversation with Bolt Threads We sat down with Bolt Threads’ Deven Dharm, Director of Software Engineering, and Patrick Johnson, Systems Analyst, to hear how Bolt uses Benchling to manage its data. With Benchling, Bolt tracks the lineage of entities and their data, significantly speeds up data entry, and eliminates data errors by 30%. Watch Now
Video Adicet Bio: Building the Next Generation of Cellular Therapies Adicet Bio is harnessing the innate allogeneic potential of gamma delta (γδ) T cells to treat solid and liquid tumors. At Benchtalk West, Adicet discussed the unique challenges in developing these cutting-edge therapeutics, and how Benchling is changing the way Adicet organizes and carries out R&D. Watch Now
Video Bolt Threads: Leveraging Data to Engineer Revolutionary, Nature-Inspired Materials Bolt Threads is harnessing proteins found in nature to create materials with both practical and revolutionary uses. At Benchtalk West, Bolt outlined how they work with Benchling to simplify R&D informatics and empower their scientists with a flexible and reliable platform. Watch Now
Video Highlights from Benchtalk West In April 2019, Benchling hosted its first West Coast User Forum: Benchtalk West. Leaders from the life sciences community gathered together to share groundbreaking research and discuss ideas about the path forward for the field. Check out this highlight reel to learn more about Benchtalk West and other upcoming Benchling events. Watch Now
Video Benchtalk West’s Panel Discussion: Making the Tough Decisions – Planning, Optimizing, and Measuring Life Science R&D At Benchtalk West 2019, a panel of life science leaders discussed the ins and outs of planning for success and scaling iterative R&D processes. Listen in to join the conversation on preparing to scale before you have data, improving iteration after iteration, and inspiring team-wide collaboration. Watch Now
Whitepaper Benchtalk Volume 1: New Paths in Life Science Read volume one of Benchtalk, a journal produced by Benchling. Benchtalk showcases the groundbreaking work of brilliant life scientists from academia to industry, facilitates discourse among members of the life sciences community, and connects them to revolutionary ideas. Learn more
Video Benchling Overview Watch an overview of the key features of Benchling Notebook, Molecular Biology, Registry, Inventory, Workflows, and Requests. Watch Now
Video Webinar: Scaling Your Biologics R&D Programs Dennis Underwood, VP of Molecular Information Systems at Agenus, and Sajith Wickramasekara, CEO and Co-Founder of Benchling, discuss best practice strategies to streamline R&D operations. Watch Now
Video Engineer Talk: Building Platforms for Scientific Research One of our engineers, Damon Doucet, discusses the challenges behind building software that unifies data across many experiments and samples, and that surfaces that data to scientists with rich permissions. Watch Now
Video Red Cell Therapeutics: Pioneering a New Era of Cellular Therapies Tiffany Chen, Director of Discovery at Rubius Therapeutics, discusses the unique data problems presented by red blood cell therapies, and how Benchling is changing the way that Rubius organizes and carries out R&D. Watch Now
Blog The Three E’s of Measurable R&D Given the rising costs, protracted timelines, and increasing complexity of large molecule R&D, scientists, group heads, and executives all need to take a data-driven approach to optimizing their own processes and decision-making. In this series, we explore a framework for scientists, group heads, and executives to measure the success of their programs. Learn more
Whitepaper Benchling: Bringing Industrialization to the Biotech Revolution Right now, we're at the start of a biotech revolution comparable to the rise of the computer in the '70s and '80s. We believe that Benchling will be the central force that drives the industrialization of the new biotech economy. Learn more
eBook What to Look for in an Informatics Platform for Biologics R&D Fundamentally, platforms that are effective for biologics R&D must be built from the ground up to address the unique nature of biologics. Learn the five critical capabilities to look for when evaluating an informatics platform for biologics R&D. Learn more
Whitepaper The Top 8 Questions Directors of Biologics R&D Struggle to Answer We spoke with Directors of R&D across the industry to identify what's top of mind for them, and what they're struggling to answer with their legacy informatics. Learn more
Whitepaper The Top 6 Questions Directors of Informatics for Biologics R&D Struggle to Answer The key success metric of informatics for R&D is improving data integrity and accessibility to support intellectual property. This is particularly important in the emerging modalities of biologics R&D. Learn more
eBook ELN Buyer’s Guide Through our market research with heads of IT and R&D, as well as various industry consultants, we’ve assembled this biology ELN-centric guide to share industry best practices for vendor evaluation. Learn more
Whitepaper Complete your R&D Transformation with Intelligent Sample Traceability The next phase of R&D transformation requires a modern, unified solution that can interlink and track the entire R&D process. Benchling’s Registry, Inventory, and Insights applications tie together experimental results and sample intelligence, so you can answer any question about your experiments and accelerate the pace of your R&D. Learn more
Whitepaper Benchling for CRISPR Screening CRISPR screening is a powerful new screening process to understand and identify genes of interest that might be responsible for certain phenotypes in cells. It is primarily a research and screening tool and uses CRISPR gene editing in a high throughput manner. This technical note demonstrates, how Benchling can support this workflow. Learn more
Whitepaper Benchling for Phage Display Technology Phage display is a relatively newer and more sophisticated platform for antibody research. It is highly complex and requires significant automation and high throughput. We are starting to see more and more enterprise customers invest in this platform. This technical note demonstrates, how Benchling can support this workflow. Learn more
Whitepaper Benchling for Hybridoma Technology Hybridoma is a foundational platform for antibody research. It is widely used by most antibody companies to generate novel monoclonal antibodies. This technical note demonstrates how Benchling can support this workflow. Learn more
Whitepaper A Foundational Platform to Accelerate Cultured Meat R&D With significant advancements in cellular agriculture, legacy R&D tools have struggled to keep up. We're providing this guide to show how Benchling can accelerate your cultured meat R&D program. Learn more
Blog Benchling Insights: Intelligence to power your R&D Benchling Insights is a new solution for life science R&D companies to make faster, more informed decisions from their data. Insights is seamlessly integrated with all Benchling applications, and enables users to query, visualize, and collaborate around high quality, structured data that resides on the platform. Learn more
eBook Adapting Lab Courses for Virtual Learning on Benchling As social distancing practices are utilized to curb COVID-19 transmission rates, university courses have been disrupted worldwide. Read our guide for transitioning your molecular biology lab course to a virtual environment with Benchling. Learn more
Video SynBioBeta | Benching & Pairwise – The Future of Agriculture Through SynBioBeta's webinar series, Benchling and Pairwise came together to discuss how gene editing allows the production of new and improved crops that are more sustainable, more nutritious, and more affordable. We also covered the challenges and opportunities for using gene editing to bring better food to market. Watch Now
Whitepaper Benchling Integration Snapshots Learn about some of the most common use cases for Benchling’s developer platform. By integrating Benchling’s natively unified applications with other data sources and repositories, you can not only cut down on scientist busywork and manual errors, but build completely novel functions to help your organization reach breakthrough discoveries faster. Learn more
Whitepaper The Benchling Enterprise Implementation Methodology In this paper, we walk through the high-level best practices we’ve developed for enterprise implementations and discuss our implementation process itself, step-by-step. The document concludes with a case study on how this implementation methodology led to organization-wide success at a top 40 pharmaceutical company. Learn more
Video Benchling for Lab Automation Demonstration In this video, we walk through a workflow where a scientist is preparing libraries using index ligation. See firsthand how Benchling for Lab Automation minimizes scientist busywork and automatically interlinks input/output samples and results data. Watch Now
Whitepaper Benchling for Lab Automation: Harness the full potential of your laboratory instruments Benchling for Laboratory Automation is a software solution to help maximize the full potential of your laboratory robotics and analytical instrumentation. With this product, Benchling enables laboratory informatics to be seamlessly integrated with laboratory instrumentation. Learn more
Whitepaper Benchling for Institutions Overview Benchling for Institutions is a secure data management platform built for academic and non-profit research institutions. In this overview, we cover how Benchling for Institutions protects scientific IP while accelerating the work of researchers. Learn more
Video Webinar: Codon Optimization with Benchling Species-specific codon usage is an important factor to consider for improving protein expression. In this webinar, we discussed Benchling’s brand new Codon Optimization tool for systematically utilizing abundant tRNAs in various target organisms. We demonstrated how this tool’s powerful functionality, integrated with our Molecular Biology application and our data management platform, can enhance your protein expression workflows. Watch Now
Case Study Bolt Threads: Optimizing Biomaterials R&D Bolt Threads is revolutionizing fabrics with bioengineered materials. Read how Bolt uses Benchling to centralize data, streamline R&D, and gain insights that drive decision making. Learn more
Blog Benchling: Bringing biointelligence to life science R&D We're thrilled to announce Benchling’s Series C fundraising, led by Menlo Ventures and joined by Lead Edge Capital and YC Continuity. In this post, we discuss our plans for Benchling as we enter this new stage of growth, and how biointelligence is crucial for the companies that are redefining modern life science. Learn more
Case Study Adicet Bio: Building a Data Infrastructure for Next-Generation Cell Therapies Adicet Bio is building the next generation of cellular therapies with gamma delta T cells. With Benchling, Adicet Bio now has a data infrastructure that ensures their data's integrity, allows them to efficiently file for IND, and is set to scale as their team grows and their research expands. Learn more
Video Sitting Down with Adicet Bio: Building a Data Infrastructure for Cellular Therapies Watch the interview with Jeannette Grant of Adicet Bio where she shares how Adicet uses Benchling to ensure their data's integrity which prepares them for IND filing and ultimately helps them bring their therapies to the clinic. Watch Now
Video Webinar: High-Throughput DNA Sequence Design for Modern Molecular Biology Workflows Successful companies have embraced the complexity of molecular biology by building collaborative teams to carry out high-throughput research. These teams urgently need automated sequence design and analysis tools. Watch this webinar to see how Benchling Bulk DNA Assembly — a tool for modeling high-throughput combinatorial cloning in silico — accelerates molecular biology workflows. Watch Now
Video A Conversation with Bolt Threads We sat down with Bolt Threads’ Deven Dharm, Director of Software Engineering, and Patrick Johnson, Systems Analyst, to hear how Bolt uses Benchling to manage its data. With Benchling, Bolt tracks the lineage of entities and their data, significantly speeds up data entry, and eliminates data errors by 30%. Watch Now
Video Adicet Bio: Building the Next Generation of Cellular Therapies Adicet Bio is harnessing the innate allogeneic potential of gamma delta (γδ) T cells to treat solid and liquid tumors. At Benchtalk West, Adicet discussed the unique challenges in developing these cutting-edge therapeutics, and how Benchling is changing the way Adicet organizes and carries out R&D. Watch Now
Video Bolt Threads: Leveraging Data to Engineer Revolutionary, Nature-Inspired Materials Bolt Threads is harnessing proteins found in nature to create materials with both practical and revolutionary uses. At Benchtalk West, Bolt outlined how they work with Benchling to simplify R&D informatics and empower their scientists with a flexible and reliable platform. Watch Now
Whitepaper How to Upgrade from Vector NTI to Benchling In the past decade, molecular biology has evolved tremendously, but sequence design software has stagnated. In this whitepaper, we discuss how you can digitally transform your molecular biology with Benchling’s modern, cloud-based platform. Learn more
Whitepaper Benchling for Gene Therapy and Gene Editing R&D Gene therapy, nucleotide therapy, and gene editing technologies encompass a wide range of products, including plasmid DNA, viral vectors, bacterial vectors, oligonucleotides (short-strand DNA and RNA), siRNA, CRISPR, ZFNs, and TALENs. These products have been of significant research interest, especially with the recent approval of breakthrough therapies like Luxturna. However, several hurdles persist for companies seeking to develop these novel therapies. Learn more
Whitepaper Benchling for Cell Therapy R&D Cell therapies such as stem cells, CAR T cells, and TCR have been of significant interest in research over the past few decades. The recent FDA approvals of CAR T therapies have led to renewed interest in the field. As companies rush to bring more novel cell therapies to the market, they face several R&D complexities. This paper outlines the critical needs and complexities of cell therapy R&D, and how Benchling has helped address these challenges for leading cell therapy companies. Learn more
Whitepaper Benchling Security Overview Benchling’s commitment to data security is central to our company. Our success depends on earning and keeping your trust, and we take that very seriously. We know that trust starts with confidence that your company’s data is safe with us. This document outlines how Benchling keeps your company's data safe. Learn more
Whitepaper Benchling for Antibody Therapeutics R&D Antibodies are an important class of therapeutic agents which have evolved significantly over the past 30 years. Antibody R&D is now more streamlined than ever, but several factors continue to contribute to its complexity. This paper outlines the critical needs and complexities faced during both research and development phases, and how Benchling has helped address these challenges for leading antibody companies. Learn more
Video Obsidian Therapeutics: Unlocking pivotal R&D answers Obsidian’s legacy sample tracking system was unintuitive and saw low scientist usage, leading to data loss and compliance concerns. Hear how Benchling’s integrated sample tracking and notetaking generated strong user adoption, improved the quality and reliability of experimental records, and empowers Obsidian to extract learnings from their data that they otherwise wouldn’t have. Watch Now
eBook Customer Success Snapshots From California, to Korea, to the Netherlands, companies developing large molecule-based products rely on Benchling to accelerate R&D and generate unprecedented business insights. In this eBook, we cover stories from Incyte, Intellia Therapeutics, Agenus, Warp Drive Bio, Zymergen, Obsidian Therapeutics, and Inhibrx. Learn more
eBook Rubius: Optimizing Cell Engineering with a Unified Informatics Platform Rubius Therapeutics is engineering therapeutic red blood cells to treat a host of diseases, using varied, complex cell engineering processes to do so. Before Benchling, it was difficult for Rubius to unify these discrete steps in cellular engineering, and it left their teams out of sync. After adopting Benchling, Rubius can now collaborate and manage their pipeline, all with one unified platform. Learn more
Case Study Synlogic: Accelerating Synthetic Biology with Fully Unified Informatics Synlogic is employing naturally occurring, non-pathogenic bacteria from the human gut microbiome by genetically altering them to function as living medicines. Previously, Synlogic’s legacy software was hindering data processing and reporting. Then Synlogic adopted Benchling, which enabled them to automate and structure their data capture in a single centralized system. Learn more
Case Study Agenus: Building a Global Informatics Infrastructure Agenus is a global biopharmaceutical company with scientific staff spread across four discovery, screening, and characterization facilities around the world. Without unified informatics systems, it was difficult for Agenus's scientists to effectively find and share information. Learn how Benchling replaced Agenus's multiple informatics systems with a single, end-to-end platform. Learn more
Case Study Zymergen: Integrating the custom solutions of a technology powerhouse Zymergen is an industrial biotechnology company with many custom software systems and algorithms. Prior to adopting Benchling, Zymergen's scientists had to enter and extract data across many siloed pieces of custom software. Today, Zymergen uses Benchling as a central platform to unite their custom tools and collaborate seamlessly across teams. Learn more
Case Study Arcturus: Enhancing research productivity by 30% Arcturus is an industry leader in RNA medicines. Without standardized molecular design tools, scientists struggled to collaborate and share their sequences. And with their legacy ELN, it took an average of 10 days for experimental data to be recorded. With Benchling, Arcturus saw a dramatic increase in scientist collaboration and reduced time to data entry by 85%. Learn more
Video Benchling Overview Watch an overview of the key features of Benchling Notebook, Molecular Biology, Registry, Inventory, Workflows, and Requests. Watch Now
Video Webinar: Scaling Your Biologics R&D Programs Dennis Underwood, VP of Molecular Information Systems at Agenus, and Sajith Wickramasekara, CEO and Co-Founder of Benchling, discuss best practice strategies to streamline R&D operations. Watch Now
Video Introducing Registry Learn how to model the complexity of any large molecule entity in Benchling Registry. From bacteria and yeast strains, to antibody complexes, Registry can manage any biological entity, reagent, instrument, and more. Watch Now
Video Introducing Requests Learn how to submit requests and link relevant input samples; prioritize requests for your teams; fulfill similar requests all at once in batches; and run reports on key metrics. Watch Now
Video Introducing Workflows Organize, optimize, and measure your R&D from early discovery to bioprocessing. Learn about Benchling's tools for workflow design, data capture, progress monitoring, and business intelligence. Watch Now
Video Benchling Codeless Configuration Learn how to configure biological entities, locations, inventories, workflows, and reports in Benchling's point-and-click interface. Never wait months for a vendor to alter your informatics platform - do it yourself in moments. Watch Now
Video Benchling Registry and Molecular Biology for Antibody Engineering Learn how our unified Registry, Molecular Biology, and Notebook applications work together to power antibody R&D. Register antibodies and chains; translate between DNA and protein sequences; analyze biochemical properties in real-time. Watch Now
Video Benchling Registry and Molecular Biology for Cell and Gene Therapy Learn how our unified applications work together to power cell and gene therapy R&D. Drag-and-drop plasmids into Notebook entries; parse sequence features to automatically register plasmids and their components. Watch Now
Video Accelerating Synthetic Biology with Fully Unified Informatics Scott Hamilton, Senior Lead Process Engineer at Synlogic, talks about how he uses Benchling to integrate bioreactors directly with informatics, and accelerate data capture and analytics. Watch Now
eBook Benchling: A Modern Informatics Platform for Large Molecule R&D Benchling is natively built to model the complexity of large molecule R&D processes. It's a lasting informatics infrastructure that drives the development of your organization's scientific platform. Learn how Benchling will help you accelerate R&D and make better business decisions. Learn more
Blog How to Pick an Electronic Laboratory Notebook Benchling has seen use of its ELN in academia more than double for the past two years, with tens of thousands of researchers now logging in every day. Learn more
Whitepaper Benchling for Growing Biotech Overview Benchling is natively built to model the complexity of biologics processes and samples and provide full experimental context across handoffs. It's a lasting informatics infrastructure that drives the development of your organization's scientific platform. Learn more
Blog To Connect or to Integrate: The Role of Informatics in the Lab Export functionality and other nominal “connectivity” features displace and stand in for actually useful functionality: meaningful integration between lab informatics software. Many informatics solutions bill themselves as integrated, but more often than not, that supposed integration falls short. Learn more
Case Study Bolt Threads: Optimizing Biomaterials R&D Bolt Threads is revolutionizing fabrics with bioengineered materials. Read how Bolt uses Benchling to centralize data, streamline R&D, and gain insights that drive decision making. Learn more
Blog Benchling: Bringing biointelligence to life science R&D We're thrilled to announce Benchling’s Series C fundraising, led by Menlo Ventures and joined by Lead Edge Capital and YC Continuity. In this post, we discuss our plans for Benchling as we enter this new stage of growth, and how biointelligence is crucial for the companies that are redefining modern life science. Learn more
Blog Announcing Benchling’s Partnership with iGEM We are excited to announce our partnership with the International Genetically Engineered Machine (iGEM) Foundation. The iGEM Foundation is an independent, non-profit organization that, like Benchling, is committed to advancing synthetic biology. Learn more
Blog The Only Path Forward for Biotech Biotech is booming, but R&D is held back by widespread inefficiencies. If biotech's going to mature in the same ways as other paradigm-shifting industries, it needs a new approach. As drugs continue to get more complex and as R&D costs continue to rise, biotech's only option is to industrialize. Learn more
Blog How to Configure Registration Systems for Large Molecule R&D From plasmids, to cell lines, to viral vectors, large molecule R&D involves many entities and parameters that have to be digitally modeled and interlinked. We've put together four guides on how to structure foundational registration systems for large molecule R&D. Learn more
Blog Why Benchling’s a Gartner “Cool Vendor”: 5 Ways to Up-Level Biologics R&D With pressure mounting on pharma to deliver new innovations faster than ever before, Benchling’s vision for measurable R&D in real-time has never been more pertinent. Read about Benchling’s five pillars to up-level your R&D organization. Learn more
Blog 6 Reasons Growing Biotechs Should Invest in Informatics Now When it comes to informatics, it’s never too early to start deriving significant organizational benefits. Informatics is as much a short-term asset for growing companies as it is a long-term investment in developing your scientific platform. Learn more
Blog Sharpening the Cutting Edge: Lab Software Platforms as a Competitive Advantage No one should be complacent with legacy software, and thankfully, some biotech companies have realized that they don't have to be. The new generation of lab software rids science of grunt work, eliminating the human hours scientists used to waste transferring data between disparate software systems. Learn more
Blog Leaving Research for Good Over the past decade, there’s been fantastic progress in the quality of scientific tools for things like sequencing, synthesis, and genome engineering. Tools for managing scientific data, however, have barely changed; the industry still runs on paper, spreadsheets, and email. Learn more
Blog CRISPR-EATING: a restriction/ligation method to inexpensively generate large sgRNA guide libraries Andy Lane and his colleagues from Rebecca Heald’s lab at UC Berkeley describe a method to create sgRNA guide libraries for less than $100. Andy shares with Benchling how it works and also provides a detailed tutorials on how you can design your own guide RNA libraries. Learn more
Blog Discovering novel CRISPR effectors and a new RNA toolbox Omar Abudayyeh and Jonathan Gootenberg detail how, to uncover novel CRISPR-associated protein families, they mined all sequenced bacterial genomes on NCBI, looking for unknown proteins that cluster near known CRISPR sites. Learn more
Blog Guidelines for base editing in mammalian cells Alexis Komor from David Liu’s lab at Harvard University details her latest findings on a base-editing mechanism with an efficiency of up to 75% using a CRISPR framework. Learn more
Blog Using Cpf1 for CRISPR Cpf1 is an RNA-guided nuclease, similar to Cas9. Here, we detail how some features of Cpf1 make it advantageous over Cas9 for certain use cases of CRISPR-based gene editing. Learn more
