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Benchling for Proteins & Peptides R&D

Track immunogenicity, model post-translational modification workflows, and manage protein and peptide candidate libraries.

New classes of proteins and peptides are of significant research interest, but companies face several hurdles

This paper outlines the critical needs and complexities of protein and peptide R&D, and how Benchling has helped address these challenges for leading protein and peptide therapeutic companies.
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Proteins and Peptides Research

  • Track safety and immunogenicity throughout research

    • Create a centralized safety profile of lead protein and peptide candidates
    • Trace safety signals back to the primary, secondary, tertiary, and quaternary structure
    • Inform candidate optimization with instant access to the most up-to-date results
  • Create protein post-translational modification and peptide modification workflows

    • Design PTM workflows to suit your expression systems and protein engineering strategies
    • Organize the inventory of post-translationally modified proteins and peptides
    • Track critical structural and functional characteristics of precursors and mutants
  • Manage libraries of protein, peptides, epitopes and other related entities

    • Create a comprehensive single source library of all your protein and peptide-related entities
    • Link physical inventory and containers to library entities
    • Track lot specific results and complete sample history from the same interface

Proteins and Peptides Development

  • Seamlessly support DOE applications in protein process development

    • Identify critical quality attributes for protein and peptide therapeutics
    • Model and execute DOE studies to thoroughly evaluate your production process
    • Define process design space
  • Mitigate development risks such as aggregation and stability early

    • Identify molecule-specific stability liabilities
    • Design and execute experiments to study development liabilities throughout R&D
    • Develop risk mitigation plans and optimized processes with access to all results
  • Reduce COGS by increasing process efficiencies

    • Map entire production process on a single platform
    • Automate time-consuming and laborious steps
    • Monitor historical and real-time process performance

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