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Cell Therapy R&D Solution

Accelerate Your Next Cell Therapy Breakthrough

Design, develop, and characterize novel cellular therapies on a unified digital platform.

Tomorrow's life-saving cell therapies demand a modern digital R&D solution

Cell therapies represent a major breakthrough in the ability to leverage the body’s own immune system to treat disease. Innovators in fields such as Tumor-Infiltrating Lymphocyte (TIL) Therapy, Engineered T Cell Receptor (TCR) Therapy, Chimeric Antigen Receptor (CAR) T Cell Therapy, and Natural Killer (NK) Cell Therapy are making this potential a reality.

Modern cell therapy R&D requires a strong digital foundation to design novel constructs, perform complex product characterizations, and track production processes from start to finish. Full traceability must be maintained across sequences, cell lines, patient donors, and engineering processes so that critical insights can be derived throughout the R&D process.

Join the hundreds of companies already using Benching

  • R&D Capabilities
  • Benefits

Cell Therapy R&D Solution

  • Produce lead binders/proteins
    Produce lead binders / proteins
    • Perform high-throughput sequence design with Bulk Assembly and ensure sequence uniqueness during registration
    • Automatically connect diverse data sets to lead scFvs and CARs with Results tables
    • Build custom dashboards to identify leads with optimal biophysical attributes
  • Generate full constructs
    Generate full constructs and reagents
    • Ensure all relevant sample information is relayed accurately to cell engineering and analytical teams
    • Ensure inventory information such as location, quantity, and check-in/check-out status is always up to date for cell-based reagents
    • Study and refine donor cell modification processes across multiple production runs
  • Characterize lead candidates
    Characterize lead candidates
    • Trace sequence-based identity and history of samples before conducting key characterization studies
    • Execute analytical assays quickly and enforce SOPs with protocols and templates
    • Correlate results from disparate tests and assays by creating custom dashboards
  • Study safety and efficacy in vivo
    Study safety and efficacy in vivo
    • Plan in vivo studies and generate study protocols with collaborative tools
    • Monitor vivarium animals and directly track study measurements and calculations
    • Automatically link assay results to tissue samples with a unified data model
Produce lead binders/proteins
Key Features
  • Perform high-throughput sequence design with Bulk Assembly and ensure sequence uniqueness during registration
  • Automatically connect diverse data sets to lead scFvs and CARs with Results tables
  • Build custom dashboards to identify leads with optimal biophysical attributes
Generate full constructs
Key Features
  • Ensure all relevant sample information is relayed accurately to cell engineering and analytical teams
  • Ensure inventory information such as location, quantity, and check-in/check-out status is always up to date for cell-based reagents
  • Study and refine donor cell modification processes across multiple production runs
Characterize lead candidates
Key Features
  • Trace sequence-based identity and history of samples before conducting key characterization studies
  • Execute analytical assays quickly and enforce SOPs with protocols and templates
  • Correlate results from disparate tests and assays by creating custom dashboards
Study safety and efficacy in vivo
Key Features
  • Plan in vivo studies and generate study protocols with collaborative tools
  • Monitor vivarium animals and directly track study measurements and calculations
  • Automatically link assay results to tissue samples with a unified data model

Cell Therapy R&D Solution

Benchling’s cell therapy R&D solution is trusted by hundreds of cell therapy innovators to accelerate their R&D. It empowers scientists to discover novel cell therapies with modern tools designed to provide complete end-to-end traceability of samples, increase throughput and efficiency, and streamline cross-team collaboration. This modern digital R&D solution combines all the capabilities expected from the latest in silico design tools, ELN, and LIMS into one intuitive package designed for cell therapy R&D.

ACCELERATE YOUR R&D
  • Increase throughput of lead binder and full construct design
    Scientists design CAR plasmids and study protein construct features with high throughput in silico design tools and sequence-aware features.
  • Streamline collaboration between lead discovery, cell engineering, analytical, and translational sciences
    Scientists hand off plasmids, cell lines, and reagents between teams, plan protein expression and optimization studies, and share characterization results with fit-for purpose collaboration tools.
  • Uncover key insights across cell engineering processes and analytical characterization
    Scientists and executives track critical cell therapy attributes across studies, optimize cell engineering processes, and monitor inventory of critical reagents and cell lines with customizable decision support tools.

Benchling delivers measurable results
for cell therapy R&D teams

  • Productivity
    60%
    Reduction in manual R&D tasks
  • Insights
    2X
    More confidence in data quality and completeness
  • Collaboration
    95%
    Improvement in cross-team data transfer
  • Informatics
    4.5x
    Typical ROI realized by Benchling customers

See Benchling's Cell Therapy R&D Solution in action

“Benchling has helped us reduce the scientists' time that goes into patent filings. People don't have to go to Excel files to see what was done when, etc.”
Vipin Suri

Vice President of Discovery

How We Deliver

  • Dedicated Expertise
    Our Customer Experience professionals possess deep scientific expertise, as well as training on information technology best practices. They apply this know-how to support cell therapy customers across a wide range of R&D teams.
  • Continuous Oversight
    Leverage Benchling's pre-implementation solutions consulting, professional implementation services, and customer success management expertise to help you get the most out of Benchling.
  • Focused R&D Support
    Take advantage of Benchling’s foundational implementation guides, developed by our Customer Experience team to support many cell therapy R&D functions, including:

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See why more than 300,000 scientists trust Benchling to power their R&D
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