Benchling for Vaccines R&D

Integrate reverse vaccinology approaches, discover novel adjuvants, and improve production yield.

Vaccines Research

Integrate reverse vaccinology approaches into vaccine antigen discovery.
- Sequence whole genomes of biological target or pathogens
- Express recombinant proteins with functional activity
- Identify novel candidate antigens
Discover novel adjuvants.
- Perform HTS and in silico screening of new adjuvant candidates for vaccines
- Characterize novel adjuvants for confirmatory activity
- Optimize new adjuvants
Leverage systems biology and other computational methods to predict the safety and the efficacy of vaccines.
- Centralize data on a single platform to analyze antigen and protective epitope sequences
- Run structural biology experiments and workflows to redesign broadly protective antigens
- Incorporate immunization results to improve computational methods

Accelerate vaccine production with synthetic technologies.
- Design custom gene and protein constructs
- Manage synthesis workflows for antigens and variants
- Maximize vaccine production with high expression and improved capacity
Characterize and test adjuvants and immuno-potentiators.
- Centralize incoming raw material characterization results
- Integrate all results from intermediates, bulk material and other downstream testing
- Build a comprehensive characterization profile of vaccine product
Continuously improve and modernize process.
- Identify and define key process performance metrics
- Integrate with production automation and monitor process continuously
- Generate actionable evidence to improve process output