wordmark

Accelerate biologics discovery with cutting-edge bioinformatics

Take sequencing data through complete bioinformatics workflows to identify and optimize promising candidates. Hits move directly into Benchling Biologics for registration and AI-ready data capture, without data wrangling at the handoff.

From sequencing run to registered candidate, in one platform

PipeBio handles the upstream work: processing NGS and Sanger data, clustering candidates, screening liabilities, and scoring hits for developability. When your team is ready to move forward, those hits go directly into Benchling Biologics with annotation intact. No exports, no reformatting, no reconciliation step.

Registration, automated sequence characterization, and lineage tracking pick up exactly where analysis leaves off, so the data your computational team needs for the next design cycle is already structured and ready.

Product Double Helix

Identify and optimize leads with advanced sequence analysis

Advance discovery

Advance cutting-edge biologics discovery 

  • Suited for antibodies, TCR, peptides, and other advanced biologics modalities 

  • Accepts all common sequence formats and platforms (e.g., Illumina, PacBio, 10X Genomics, Sanger)

  • Combine sequence data with functional data (e.g. ELISA, SPR)

Run workflows

Run end-to-end bioinformatics workflows

  • Run pre-processing and quality control steps (e.g. PCR error correction, assembly, merging)

  • Perform labeling, annotation, and clustering

  • Use out-of-the-box visualizations to support lead selection and optimization

Connect your data

Operate on a scalable, extensible, cloud platform

  • Move hits directly into Benchling Biologics for format-aware registration and automated sequence characterization

  • Automate workflows to simplify and standardize analyses

  • Use REST APIs and SDK for full programmatic control

A comprehensive suite of sequence analysis tools

  • Easy to use workflow editor

    Configure custom workflows and tailor individual tools and parameters for extracting desired sequences. Automatically create custom standard reports for a quick overview of your analysis results.

  • Annotations

    Accurately annotate, define and characterize regions and liabilities of antibody sequences to de-risk antibody development.

  • Clustering

    Cluster by defining your clonotype, identify clonal families and compare sample types across experiments, analyze enrichment and explore clusters visually with cluster network plots. 

  • Hit picking

    Create phylogenetic trees, identify the most diverse sequences in your sample and hit-pick to express in vector and characterize your antibody sequences.

  • Out-of-the-box visualizations 

    Analyze your sequences visually with amino acid barcharts, cluster diagrams and phylogenetic trees.

  • Bulk APIs and SDK

    Use the API to programmatically upload and export sequences and manage users. Integrate PipeBio with your IT infrastructure and move annotated hits directly into Benchling Biologics for registration and downstream experimental data capture.

Powering breakthroughs for over 1,300 biotechnology companies

Helix Image