
Blog post
Take sequencing data through complete bioinformatics workflows to identify and optimize promising candidates. Hits move directly into Benchling Biologics for registration and AI-ready data capture, without data wrangling at the handoff.
PipeBio handles the upstream work: processing NGS and Sanger data, clustering candidates, screening liabilities, and scoring hits for developability. When your team is ready to move forward, those hits go directly into Benchling Biologics with annotation intact. No exports, no reformatting, no reconciliation step.
Registration, automated sequence characterization, and lineage tracking pick up exactly where analysis leaves off, so the data your computational team needs for the next design cycle is already structured and ready.

Suited for antibodies, TCR, peptides, and other advanced biologics modalities
Accepts all common sequence formats and platforms (e.g., Illumina, PacBio, 10X Genomics, Sanger)
Combine sequence data with functional data (e.g. ELISA, SPR)
Run pre-processing and quality control steps (e.g. PCR error correction, assembly, merging)
Perform labeling, annotation, and clustering
Use out-of-the-box visualizations to support lead selection and optimization
Move hits directly into Benchling Biologics for format-aware registration and automated sequence characterization
Automate workflows to simplify and standardize analyses
Use REST APIs and SDK for full programmatic control
Configure custom workflows and tailor individual tools and parameters for extracting desired sequences. Automatically create custom standard reports for a quick overview of your analysis results.
Accurately annotate, define and characterize regions and liabilities of antibody sequences to de-risk antibody development.
Cluster by defining your clonotype, identify clonal families and compare sample types across experiments, analyze enrichment and explore clusters visually with cluster network plots.
Create phylogenetic trees, identify the most diverse sequences in your sample and hit-pick to express in vector and characterize your antibody sequences.
Analyze your sequences visually with amino acid barcharts, cluster diagrams and phylogenetic trees.
Use the API to programmatically upload and export sequences and manage users. Integrate PipeBio with your IT infrastructure and move annotated hits directly into Benchling Biologics for registration and downstream experimental data capture.